SCHEMBL2732228

SCHEMBL2732228

CC(C)c1nccnc1C(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30202366 0.82 CYP2A6 (0.30)
SCHEMBL20154935 0.82 TSHR (0.31)
SCHEMBL2742986 0.80
SCHEMBL21737018 0.80
SCHEMBL27319066 0.80
SCHEMBL9900250 0.80 NOS3 (0.36)
SCHEMBL16431582 0.80
SCHEMBL29427912 0.80 NOS3 (0.36)
SCHEMBL2742982 0.80 CCNB2 (0.30)
SCHEMBL26023870 0.80 PIK3CG (0.31) PIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685778-B Method for synthesizing long-circulating cationic liposome 苏州艾博生物科技有限公司 2023-10-17 CN claimed
CN-114685778-A Synthesis method of long-circulating cationic liposome 苏州艾博生物科技有限公司 2022-07-01 CN claimed
US-20220135613-A1 METHOD FOR PREPARING DRUG TOXIN PNU-159682 FOR ANTIBODY DRUG CONJUGATE, AND INTERMEDIATES THEREIN LEVENA BIOPHARMA CO LTD (CN) 2022-05-05 US claimed
EP-3907223-A1 METHOD FOR PREPARING DRUG TOXIN PNU-159682 OF ANTIBODY DRUG CONJUGATE, AND INTERMEDIATE THEREIN Levena Biopharma Co., Ltd. (CN) 2021-11-10 EP claimed
CN-110776501-B Preparation method of drug toxin PNU-159682 for antibody drug conjugate and intermediate thereof 联宁(苏州)生物制药有限公司 2021-04-02 CN claimed
WO-2021031599-A1 METHOD FOR PREPARING DRUG TOXIN PNU-159682 OF ANTIBODY DRUG CONJUGATE, AND INTERMEDIATE THEREIN 联宁(苏州)生物制药有限公司 2021-02-25 WO claimed
CN-110776501-A Preparation method of drug toxin PNU-159682 for antibody drug conjugate and intermediate thereof 联宁(苏州)生物制药有限公司 2020-02-11 CN claimed
US-7316826-B2 Coffee aroma with improved stability SYMRISE GMBH & CO. KG (DE) 2008-01-08 US claimed
US-20040202767-A1 Coffee aroma with improved stability SYMRISE AG (DE) 2004-10-14 US claimed
US-20240228488-A1 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN TAKEDA PHARMACEUTICALS CO (JP) 2024-07-11 US disclosed
US-20240226106-A1 INHIBITORS OF PLASMA KALLIKREIN SHIRE HUMAN GENETIC THERAPIES (US) 2024-07-11 US disclosed
EP-3790886-B1 KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER AMGEN INC (US) 2024-06-26 EP disclosed
US-11807621-B2 Compounds and compositions for use in treating skin disorders KAMARI PHARMA LTD. (IL) 2023-11-07 US disclosed
US-20230340055-A1 GLYCOSYLATED IL-2 PROTEINS AND USES THEREOF Ascendis Pharma Oncology Division A/S (DK) 2023-10-26 US disclosed
EP-1329495-A2 Gas odorization HAARMANN & REIMER GMBH (DE) 2003-07-23 EP disclosed
EP-1109881-B1 GAS ODORIZATION METHOD HAARMANN & REIMER GMBH (DE) 2003-03-05 EP disclosed
EP-1109881-A1 GAS ODORIZATION METHOD HAARMANN & REIMER GMBH (DE) 2001-06-27 EP disclosed
WO-2000011120-A1 GAS ODORIZATION METHOD HAARMANN & REIMER GMBH (DE) 2000-03-02 WO disclosed
EP-0619317-A1 An expeditious synthesis of C-disaccharides using a temporary ketal connection CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1994-10-12 EP disclosed
EP-0309203-A2 Flavorant-release additives and compositions containing them Philip Morris Products Inc. (US) 1989-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340055-A1 GLYCOSYLATED IL-2 PROTEINS AND USES THEREOF IL2, IL1A, ILF2 PIK3CG 4687/4885
US-20220135613-A1 METHOD FOR PREPARING DRUG TOXIN PNU-159682 FOR ANTIBODY DRUG CONJUGATE, AND INTERMEDIATES THEREIN ANTXR2, TNNT2, SLC47A2 PIK3CG 3619/4885
US-20240228488-A1 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK5, KLK1 PIK3CG 1378/4885
US-20240226106-A1 INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK5, KLK1 PIK3CG 1426/4885
US-11807621-B2 Compounds and compositions for use in treating skin disorders RDX, HAX1, F12 PIK3CG 3741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.