Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545203 | 0.86 | MEN1 (0.47) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL6720918 | 0.79 | MEN1 (0.51) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL27453440 | 0.79 | KDR (0.49) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL6727687 | 0.78 | SIGMAR1 (0.51) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL27424513 | 0.77 | HSD17B1 (0.40) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL6720634 | 0.76 | MEN1 (0.51) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL6727685 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL6728001 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL6719746 | 0.75 | ALDH1A1 (0.45) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL6724367 | 0.74 | MEN1 (0.49) | MEN1KMT2ATP53GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1126434-A | Therapeutic substituted guanidines | CAMBRIDGE NEUROSCIENCE INC (US) | 1996-07-10 | — | — | CN | claimed |
| CN-1126434-A | Therapeutic substituted guanidines | CAMBRIDGE NEUROSCIENCE INC (US) | 1996-07-10 | — | — | CN | disclosed |