Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TACR2 | P21452 | 4/20 | 0.53 |
| ▸ | SRC | P12931 | 9/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27430034 | 0.87 | HTR2C (0.48) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27429987 | 0.77 | MAPT (0.48) | LMNASMN1; SMN2MAPTSRCHTR2A | |
| SCHEMBL3645171 | 0.77 | HTR2C (0.58) | MAPTHTR2AHTR2C | |
| SCHEMBL27430032 | 0.76 | HTR2C (0.60) | TACR2SRCHTR2AHTR2C | |
| SCHEMBL27429988 | 0.76 | HTR2C (0.61) | HTR2AHTR2C | |
| SCHEMBL27248311 | 0.75 | HPGD (0.58) | MAPTHTR2AHTR2CABL1 | |
| SCHEMBL11812589 | 0.75 | LMNA (0.94) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23867520 | 0.74 | TDP1 (0.48) | SMN1; SMN2MAPT | |
| SCHEMBL27248309 | 0.74 | SRC (0.52) | LMNATACR2SRCHTR2AHTR2C | |
| SCHEMBL27248330 | 0.74 | L3MBTL1 (0.58) | LMNASMN1; SMN2MAPTSRCHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |