Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248652 | 0.99 | ENPP2 (0.60) | ENPP2DGAT2HPGDMAPTLMNA | |
| SCHEMBL18256373 | 0.90 | KLK7 (0.57) | HPGDMAPTLMNASMN1; SMN2HDAC3 | |
| SCHEMBL10682388 | 0.90 | TP53 (0.58) | HPGDMAPTLMNASMN1; SMN2HTT | |
| SCHEMBL18256371 | 0.89 | KLK7 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18256354 | 0.89 | HPGD (0.54) | ENPP2DGAT2HPGDMAPTLMNA | |
| SCHEMBL18256332 | 0.87 | ALDH1A1 (0.58) | HPGDMAPTLMNASMN1; SMN2HDAC10 | |
| SCHEMBL11237810 | 0.86 | ENPP2 (0.59) | ENPP2DGAT2HPGDMAPTLMNA | |
| SCHEMBL9524719 | 0.86 | ENPP2 (0.61) | ENPP2DGAT2HPGDLMNASMN1; SMN2 | |
| SCHEMBL11467992 | 0.85 | HDAC3 (0.56) | MAPTSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL18256355 | 0.85 | HDAC3 (0.56) | MAPTSMN1; SMN2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1111453-A | Aryl sulfonamide derivatives and pharmaceutical compositions containing the same | NIPPON KOKAN KK (JP) | 1995-11-08 | — | — | CN | disclosed |