Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.60 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.53 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.53 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.53 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.53 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.53 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.53 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.53 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.53 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27430785 | 0.99 | ENPP2 (0.58) | ENPP2DGAT2HPGDPSMB11PSMA7 | |
| SCHEMBL18256371 | 0.91 | KLK7 (0.56) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL18256354 | 0.90 | HPGD (0.54) | ENPP2DGAT2HPGDMAPTLMNA | |
| SCHEMBL18256373 | 0.89 | KLK7 (0.57) | HPGDMAPTLMNASMN1; SMN2HDAC3 | |
| SCHEMBL10682388 | 0.89 | TP53 (0.58) | HPGDMAPTLMNASMN1; SMN2HTT | |
| SCHEMBL11237810 | 0.88 | ENPP2 (0.59) | ENPP2DGAT2HPGDPSMB11PSMA7 | |
| SCHEMBL9524719 | 0.88 | ENPP2 (0.61) | ENPP2DGAT2HPGDPSMB11PSMA7 | |
| SCHEMBL11467992 | 0.86 | HDAC3 (0.56) | MAPTSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL18256355 | 0.86 | HDAC3 (0.56) | MAPTSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL18256332 | 0.86 | ALDH1A1 (0.58) | HPGDMAPTLMNASMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2018-05-24 | — | — | US | disclosed |
| EP-3307746-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | National and Kapodistrian Universty of Athens (GR) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016184561-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2016-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SPINT2, SERPINB1 | ENPP2 1/4885DGAT2 1276/4885HPGD 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.