SCHEMBL2743086

SCHEMBL2743086

Cn1nc(C(C)(C)C)c(C#N)c1N

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.37
KMT2A Q03164 1/20 0.37
POLB P06746 1/20 0.33
LRRK2 Q5S007 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 3/20 0.33
MAPT P10636 2/20 0.33
NCOA1 Q15788 2/20 0.33
NCOA3 Q9Y6Q9 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9518977 0.83 LMNA (0.54) LMNAKMT2APOLBLRRK2L3MBTL1
SCHEMBL8914855 0.79 HPGD (0.33) SMN1; SMN2GAATSHR
SCHEMBL12636842 0.78 CCNT1 (0.32) LMNAKMT2APOLBMAPT
SCHEMBL12636699 0.78 CCNT1 (0.32) LMNAKMT2APOLBMAPT
SCHEMBL12636833 0.75 MAPT (0.34) KMT2APOLBMAPTGAA
SCHEMBL11543788 0.75 LMNA (0.41) LMNAKMT2APOLBLRRK2HTT
SCHEMBL2743085 0.75 GAA (0.38) LMNAKMT2ALRRK2MAPTALDH1A1
SCHEMBL1821874 0.74 TSHR (0.47) LMNAKMT2APOLBLRRK2MAPT
SCHEMBL11698200 0.74 KMT2A (0.41) LMNAKMT2APOLBLRRK2L3MBTL1
SCHEMBL12636838 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245472-A1 COMPOUNDS AND RELATED METHODS USEFUL FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES REMIX THERAPEUTICS INC. (US) 2025-11-27 WO disclosed
US-8202327-B2 Pigment composition, inkjet recording ink, coloring composition for color filter, and color filter FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
US-20120001133-A1 PIGMENT COMPOSITION, INKJET RECORDING INK, COLORING COMPOSITION FOR COLOR FILTER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-01-05 US disclosed