Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743086 | 0.83 | LMNA (0.37) | LMNAKMT2AL3MBTL1HTTMAPT | |
| SCHEMBL13184169 | 0.79 | LMNA (0.55) | LMNAKMT2AL3MBTL1HTTMAPT | |
| SCHEMBL11543788 | 0.78 | LMNA (0.41) | LMNAKMT2AHTTMAPTALDH1A1 | |
| SCHEMBL6744945 | 0.78 | LMNA (0.58) | LMNAKMT2AL3MBTL1HTTMAPT | |
| SCHEMBL4625127 | 0.78 | LMNA (0.54) | LMNAKMT2AL3MBTL1HTTMAPT | |
| SCHEMBL16402642 | 0.75 | LMNA (0.51) | LMNAKMT2AL3MBTL1HTTMAPT | |
| SCHEMBL1821874 | 0.72 | TSHR (0.47) | LMNAKMT2AMAPTALDH1A1POLB | |
| SCHEMBL11698200 | 0.72 | KMT2A (0.41) | LMNAKMT2AL3MBTL1HTTMAPT | |
| SCHEMBL28399750 | 0.72 | POLB (0.51) | LMNAKMT2AL3MBTL1HTTMAPT | |
| SCHEMBL15942159 | 0.72 | POLB (0.51) | LMNAKMT2AL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561836-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010480-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | claimed |
| EP-3046156-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE AND DISPLAY DEVICE EACH COMPRISING THE ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2016-07-20 | — | — | EP | disclosed |