SCHEMBL2743097

SCHEMBL2743097

Cc1ccc(NC(=O)c2cc3ccccc3cc2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 1.00
NPC1 O15118 6/20 1.00
RAB9A P51151 6/20 1.00
POLB P06746 5/20 1.00
MEN1 O00255 5/20 1.00
ALPL P05186 1/20 0.77
ALPI P09923 1/20 0.77
ALPG P10696 1/20 0.77
CASP3 P42574 1/20 0.74
SENP7 Q9BQF6 1/20 0.74
SENP6 Q9GZR1 1/20 0.74
MAPT P10636 1/20 0.68
MAPK1 P28482 1/20 0.68
APOBEC3A P31941 1/20 0.68
APOBEC3G Q9HC16 1/20 0.68
PLG P00747 3/20 0.68
KLK1 P06870 2/20 0.68
KLK6 Q92876 2/20 0.68
AHR P35869 1/20 0.68
LMNA P02545 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30637144 1.00 KMT2A (1.00) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL29440791 1.00 KMT2A (1.00) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL5426499 0.92 KMT2A (0.84) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL27655663 0.88 POLB (0.79) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL9291851 0.88 KMT2A (0.78) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL27977469 0.88 KMT2A (0.78) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL14328963 0.87 KMT2A (0.77) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL15478030 0.87 KMT2A (0.77) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL30084384 0.87 MEN1 (0.77) KMT2ANPC1RAB9APOLBMEN1
SCHEMBL29890853 0.87 MEN1 (0.77) KMT2ANPC1RAB9APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085543-B Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2023-11-07 CN claimed
CN-114085543-A Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2022-02-25 CN claimed
EP-0485474-A1 A METHOD AND A SYSTEM FOR QUANTITATIVELY MONITORING A CHEMICAL COMPONENT DISSOLVED IN A LIQUID MEDIUM. KOEGE KEMISK VAERK (DK) 1992-05-20 EP claimed
WO-1991002254-A1 A METHOD AND A SYSTEM FOR QUANTITATIVELY MONITORING A CHEMICAL COMPONENT DISSOLVED IN A LIQUID MEDIUM KEMISK VÆRK KØGE A/S (DK) 1991-02-21 WO claimed
CN-114085543-B Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2023-11-07 CN disclosed
CN-114085543-A Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2022-02-25 CN disclosed
US-8969339-B2 Compositions and methods for bone formation and modeling ENZO BIOCHEM, INC. (US) 2015-03-03 US disclosed
US-20140329863-A1 NOVEL ANTIPRION COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-11-06 US disclosed
US-20130172332-A1 COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING ENZO BIOCHEM, INC. (US) 2013-07-04 US disclosed
US-8454710-B2 Process for producing azo compounds, pigment dispersion, coloring composition, ink for inkjet recording, coloring composition for color filter, and color filter FUJIFILM CORPORATION (JP) 2013-06-04 US disclosed
US-20120328984-A1 PROCESS FOR PRODUCING AZO COMPOUNDS, PIGMENT DISPERSION, COLORING COMPOSITION, INK FOR INKJET RECORDING, COLORING COMPOSITION FOR COLOR FILTER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-12-27 US disclosed
US-8202327-B2 Pigment composition, inkjet recording ink, coloring composition for color filter, and color filter FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
WO-1991002254-A1 A METHOD AND A SYSTEM FOR QUANTITATIVELY MONITORING A CHEMICAL COMPONENT DISSOLVED IN A LIQUID MEDIUM KEMISK VÆRK KØGE A/S (DK) 1991-02-21 WO disclosed
EP-0190947-B1 PROCESS FOR PRODUCING AZO PIGMENTS Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1990-01-31 EP disclosed
US-4842979-A WITH A DIAZONIUM SALT, 2-HYDROXY-3-NAPHTHOIC ANILIDE, 2-HYDROXY-3-NAPHTHOIC AMIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-06-27 US disclosed
US-4713307-A 2,7-BIS(1'-AZO-2'-HYDROXY-3'-NAPHTHANILIDE)NAPHTHALENES, AND HOLE TRANSPORT LAYER XEROX CORPORATION (US) 1987-12-15 US disclosed
US-4655844-A COUPLING AROMATIC DIAZONIUM COMPOUND WITH 3-HYDROXY-2-NAPHTHOIC ACID AND A BIS-NAPHTHYLAMETHANE KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1987-04-07 US disclosed
EP-0190947-A2 Process for producing azo pigments Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1986-08-13 EP disclosed
US-4221709-A Azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1980-09-09 US disclosed
US-3947515-A Process for the preparation of pure, aromatic o-hydroxy-carboxylic acid aryl amides HOECHST AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172332-A1 COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING LRP6, BMP6, WNT3A KMT2A 4661/4885NPC1 1344/4885RAB9A 2017/4885
US-20140329863-A1 NOVEL ANTIPRION COMPOUNDS PRNP, PSEN1, PSEN2 KMT2A 4582/4885NPC1 57/4885RAB9A 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.