Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 7/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173564 | 0.79 | MEP1B (0.66) | MEP1BPARP1IDH1BRD4BRD3 | |
| SCHEMBL28822119 | 0.79 | KCNH2 (0.50) | MEP1BPARP1IDH1LMNATSHR | |
| SCHEMBL20668077 | 0.75 | PARP1 (0.52) | MEP1BPARP1IDH1MEN1KMT2A | |
| SCHEMBL21172166 | 0.74 | KCNH2 (0.48) | LMNAMAPTCHRM2CHRM4CHRM1 | |
| SCHEMBL45866 | 0.72 | PARP1 (0.57) | MEP1BPARP1IDH1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL27603084 | 0.71 | PARP1 (0.55) | MEP1BPARP1IDH1TSHRMAPT | |
| SCHEMBL31487553 | 0.70 | PARP1 (0.53) | MEP1BPARP1IDH1FOLH1 | |
| SCHEMBL7771633 | 0.70 | PARP1 (0.53) | MEP1BPARP1IDH1FOLH1 | |
| SCHEMBL30969284 | 0.69 | ESR1 (0.64) | PARP1LMNATSHRMAPTMEN1 | |
| SCHEMBL2108942 | 0.69 | MEP1B (0.59) | MEP1BPARP1IDH1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |