Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194309 | 0.83 | SPHK2 (0.52) | MEP1BCYP4F2CYP4A11PARP1FOLH1 | |
| SCHEMBL8173564 | 0.83 | MEP1B (0.66) | MEP1BPARP1BCHEIDH1 | |
| SCHEMBL10669113 | 0.81 | SPHK2 (0.57) | CYP4F2CYP4A11PARP1SPHK2SPHK1 | |
| SCHEMBL15964806 | 0.80 | SPHK2 (0.60) | CYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL9356792 | 0.80 | SPHK2 (0.60) | CYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL28241905 | 0.80 | SPHK2 (0.60) | CYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL2822360 | 0.80 | PARP1 (0.50) | OPRM1MEN1KMT2AMEP1BCYP4F2 | |
| SCHEMBL31487553 | 0.79 | PARP1 (0.53) | MEP1BCYP4F2CYP4A11PARP1FOLH1 | |
| SCHEMBL7771633 | 0.79 | PARP1 (0.53) | MEP1BCYP4F2CYP4A11PARP1FOLH1 | |
| SCHEMBL274323 | 0.79 | MEP1B (0.45) | CHRM2CHRM1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903293-A | Novel anti-invasive compounds | ABIVAX | 2015-09-09 | — | — | CN | disclosed |