Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22446850 | 0.73 | CHRNB2 (0.54) | ALDH1A1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL1412935 | 0.72 | — | — | |
| SCHEMBL19546492 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNASLC15A2CHRM1CHRNB2 | |
| SCHEMBL28655640 | 0.70 | — | — | |
| SCHEMBL27009155 | 0.68 | ALDH1A1 (0.38) | ALDH1A1LMNASLC15A2CHRM1CHRNB2 | |
| SCHEMBL23463132 | 0.67 | ALDH1A1 (0.36) | ALDH1A1LMNASLC15A2CHRM1CHRNB2 | |
| SCHEMBL7541851 | 0.66 | — | — | |
| SCHEMBL3790342 | 0.66 | CA1 (0.57) | ALDH1A1LMNASLC15A2PAOXACHE | |
| SCHEMBL9720153 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2CHRM1PAOX | |
| SCHEMBL14860086 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1102596-C | 5H-thiazole [3,2-a] pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 2003-03-05 | — | — | CN | disclosed |
| CN-1206010-A | 5H-thiazole [3,2-a] pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 1999-01-27 | — | — | CN | disclosed |