SCHEMBL27433007

SCHEMBL27433007

O=P(Cl)(Cl)Cl.O=P(Cl)(Cl)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA5A P35218 1/20 0.50
CFTR P13569 1/20 0.44
ALDH1A1 P00352 4/20 0.42
GAA P10253 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALPG P10696 1/20 0.42
ALOX12 P18054 1/20 0.42
NPY1R P25929 1/20 0.42
HTT P42858 1/20 0.42
NPY2R P49146 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TSHR P16473 2/20 0.41
ALOX15 P16050 1/20 0.41
USP2 O75604 1/20 0.41
ESR1 P03372 1/20 0.41
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28809780 0.97 CA2 (0.52) CA2CA4CA5ACFTRALDH1A1
SCHEMBL140712 0.97 CA2 (0.52) CA2CA4CA5ACFTRALDH1A1
Carbon Tetrachloride SCHEMBL28663038 0.89 CA2 (0.46) CA2CA4CA5ACFTRALDH1A1
Chloroform SCHEMBL28441982 0.89 CA2 (0.46) CA2CA4CA5ACFTRALDH1A1
Urea SCHEMBL11426798 0.85 CA2 (0.48) CA2CA4CA5ACFTRALDH1A1
Phenylphosphonic Acid SCHEMBL29788868 0.85 CA2 (0.76) CA2CA4CA5ACFTRALDH1A1
SCHEMBL824518 0.81 CYP1A2 (0.46) CA2CA4CA5AALDH1A1GAA
SCHEMBL12353492 0.81 HPGD (0.36) CA2CA4CA5AGAATSHR
Tetrahydrofuran SCHEMBL28809270 0.79 GAA (0.42) CA2CA4CA5ACFTRALDH1A1
SCHEMBL95882 0.79 CA2 (0.52) CA2CA4CA5ACFTRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1105499-C Improved synthesis process of pesticide synergist containing propyne organophosphate SHANGHAI INST OF ENTOMOLOGY CH (CN) 2003-04-16 CN disclosed
CN-1183896-A Improved synthesis process of pesticide synergist containing propyne organophosphate SHANGHAI INST OF ENTOMOLOGY CH (CN) 1998-06-10 CN disclosed