SCHEMBL824518

SCHEMBL824518

O=P(Cl)(Cl)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
ALDH1A1 P00352 2/20 0.45
ACP3 P15309 2/20 0.43
PTPN5 P54829 1/20 0.42
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
MGLL Q99685 1/20 0.41
TAAR1 Q96RJ0 2/20 0.40
MAPK1 P28482 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
CYP3A4 P08684 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MMP3 P08254 1/20 0.40
BCL2L1 Q07817 1/20 0.40
MMP8 P22894 1/20 0.39
MMP14 P50281 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14245147 0.85 ACP3 (0.47) CYP1A2ALDH1A1ACP3PTPN5CA2
Benzene SCHEMBL28274900 0.84 CA2 (0.52) ALDH1A1CA2TDP1CA4CA5A
SCHEMBL140712 0.84 CA2 (0.52) ALDH1A1CA2TDP1CA4CA5A
SCHEMBL28809780 0.84 CA2 (0.52) ALDH1A1CA2TDP1CA4CA5A
SCHEMBL17711516 0.83 ACP3 (0.52) CYP1A2ALDH1A1ACP3PTPN5CA2
SCHEMBL27433007 0.81 CA2 (0.50) ALDH1A1CA2TDP1CA4CA5A
SCHEMBL11145592 0.81 ALDH1A1 (0.53) CYP1A2ALDH1A1ACP3PTPN5CA2
SCHEMBL14339266 0.81 ALDH1A1 (0.53) CYP1A2ALDH1A1ACP3PTPN5CA2
SCHEMBL14339275 0.81 ALDH1A1 (0.53) CYP1A2ALDH1A1ACP3PTPN5CA2
Biphenyl SCHEMBL122229 0.81 ALDH1A1 (0.60) CYP1A2ALDH1A1ACP3PTPN5CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926175-A Halogen-free polyphosphate flame retardant with high polymerization degree and preparation method thereof 缔久高科技材料(南通)有限公司 2023-04-07 CN disclosed
EP-3541890-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-28 EP disclosed
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-11-21 US disclosed
WO-2018091435-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-05-24 WO disclosed
US-8865321-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-21 US disclosed
US-8865321-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-21 US disclosed
EP-1669398-B1 FLAME-RETARDANT PROCESSED RESIN OBTAINED WITH A REACTIVE FLAME RETARDANT FUJI ELECTRIC CO LTD (JP) 2014-01-08 EP disclosed
EP-2344607-B1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-04-10 EP disclosed
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-20100047480-A1 CELLULOSE ESTER PELLETS, CELLULOSE ESTER FILM, MANUFACTURING METHOD OF CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY C/O KONICA MINOLTA OPTO, INC. (JP) 2010-02-25 US disclosed
US-7557152-B2 Reactive flame retardant and flame-retardant resin processed article FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2009-07-07 US disclosed
US-20090043032-A1 REACTIVE FLAME RETARDANT AND FLAME-RETARDANT RESIN PROCESSED ARTICLE FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2009-02-12 US disclosed
EP-1852489-A1 REACTIVE FLAME RETARDANT AND FLAME-RETARDANT RESIN PROCESSED ARTICLE FUJI ELECTRIC HOLDINGS CO., LTD.; (JP) 2007-11-07 EP disclosed
EP-1669398-A1 REACTIVE FLAME RETARDANT AND FLAME-RETARDANT PROCESSED RESIN OBTAINED WITH THE SAME FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2006-06-14 EP disclosed
EP-1303527-B1 MATRIX METALLOPROTEINASE INHIBITORS LEO PHARMA AS (DK) 2004-09-29 EP disclosed
EP-1303527-A1 MATRIX METALLOPROTEINASE INHIBITORS Leo Pharma A/S (DK) 2003-04-23 EP disclosed
US-6521606-B2 2-(4-Chlorophenoxy)-2-oxo-1,3,2-oxazaphosphorinane-3-aceto -hydroxamic acid, for example; antiathritic, -tumor, -metastasis, -proliferative and -ulcer agents; multiple sclerosis; vision defects; skin disorders LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 2003-02-18 US disclosed
US-20020103166-A1 Matrix metalloproteinase inhibitors LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 2002-08-01 US disclosed
WO-2002006293-A1 MATRIX METALLOPROTEINASE INHIBITORS LEO PHARMA A/S (DK) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043032-A1 REACTIVE FLAME RETARDANT AND FLAME-RETARDANT RESIN PROCESSED ARTICLE F11, PF4, RXRA CYP1A2 1727/4885ALDH1A1 2920/4885ACP3 747/4885
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM CYP1A2 441/4885ALDH1A1 33/4885ACP3 3512/4885
US-20020103166-A1 Matrix metalloproteinase inhibitors MMP1, MMP9, MMP8 CYP1A2 1649/4885ALDH1A1 411/4885ACP3 2577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.