Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28809270

C1CCOC1.O=P(Cl)(Cl)c1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 4/20 0.40
NPSR1 Q6W5P4 4/20 0.38
MAPK1 P28482 2/20 0.38
TSHR P16473 1/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
CA5A P35218 2/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
CFTR P13569 1/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140712 0.82 CA2 (0.52) GAAALDH1A1NPSR1TSHRCA2
Benzene SCHEMBL28274900 0.82 CA2 (0.52) GAAALDH1A1NPSR1TSHRCA2
SCHEMBL28809780 0.82 CA2 (0.52) GAAALDH1A1NPSR1TSHRCA2
SCHEMBL27433007 0.79 CA2 (0.50) GAAALDH1A1NPSR1TSHRCA2
Phenylphosphonic Acid SCHEMBL29224506 0.78 CA2 (0.64) GAASMN1; SMN2ALDH1A1NPSR1MAPK1
Carbon Tetrachloride SCHEMBL28663038 0.75 CA2 (0.46) GAAALDH1A1NPSR1TSHRCA2
Chloroform SCHEMBL28441982 0.75 CA2 (0.46) GAAALDH1A1NPSR1TSHRCA2
Tetrahydrofuran SCHEMBL28437095 0.75 SRC (0.44) NPSR1CA2CA4CA5ACA12
Piperazine SCHEMBL28087388 0.72 CA2 (0.39) GAAALDH1A1NPSR1TSHRCA2
Phenylphosphonic Acid SCHEMBL29788868 0.71 CA2 (0.76) GAAALDH1A1TSHRCA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117987072-A B1-level flame-retardant single-component polyurethane joint mixture and preparation method thereof 三棵树(上海)新材料研究有限公司 2024-05-07 CN claimed
CN-117987072-A B1-level flame-retardant single-component polyurethane joint mixture and preparation method thereof 三棵树(上海)新材料研究有限公司 2024-05-07 CN disclosed
CN-114835905-B Polyphosphazene amide metal complex catalyst for catalytic polymerization and preparation method thereof 常州巨德新材料有限公司 2023-03-31 CN disclosed
CN-114835905-A Polyphosphazene amide metal complex catalyst for catalytic polymerization and preparation method thereof 常州巨德新材料有限公司 2022-08-02 CN disclosed