Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954100 | 1.00 | HTR1A (0.45) | HTR1AHTR2CALOX5CYP11B2CYP11B1 | |
| SCHEMBL30954116 | 0.85 | HTR1A (0.46) | HTR1AHTR2CALOX5CYP11B2CYP11B1 | |
| SCHEMBL13849355 | 0.85 | HTR1A (0.46) | HTR1AHTR2CALOX5CYP11B2CYP11B1 | |
| SCHEMBL4103368 | 0.82 | HTR1A (0.45) | HTR1AHTR2CALOX5CYP11B2CYP11B1 | |
| SCHEMBL27432475 | 0.82 | HTR1A (0.45) | HTR1AHTR2CCYP11B2CYP11B1PDE3B | |
| SCHEMBL6619979 | 0.80 | LMNA (0.54) | HTR1AHTR2CCYP11B2CYP11B1PDE3B | |
| SCHEMBL30659587 | 0.79 | HTR1A (0.45) | HTR1AHTR2CCYP11B2CYP11B1PDE3B | |
| SCHEMBL26654576 | 0.79 | HTR1A (0.45) | HTR1AHTR2CCYP11B2CYP11B1PDE3B | |
| SCHEMBL29209156 | 0.79 | PDE3B (0.43) | HTR1AHTR2CALOX5CYP11B2CYP11B1 | |
| SCHEMBL27432572 | 0.79 | CYP11B2 (0.42) | HTR1AHTR2CALOX5CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121130-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2024-06-13 | — | — | WO | disclosed |