Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954097 | 1.00 | POLB (0.47) | POLBRXFP1PDE10AKMT2AALDH1A1 | |
| SCHEMBL30954136 | 0.83 | RXFP1 (0.56) | POLBRXFP1PDE10AKMT2APKM | |
| SCHEMBL27434483 | 0.83 | RXFP1 (0.56) | POLBRXFP1PDE10AKMT2APKM | |
| SCHEMBL27432476 | 0.81 | RXFP1 (0.46) | POLBRXFP1PDE10AKMT2ANPC1 | |
| SCHEMBL13382355 | 0.79 | DRD2 (0.47) | POLBALDH1A1NPC1PKMPKLR | |
| SCHEMBL1494287 | 0.79 | RXFP1 (0.45) | POLBRXFP1PDE10AKMT2AALDH1A1 | |
| SCHEMBL31017016 | 0.78 | RXFP1 (0.46) | POLBRXFP1PDE10AKMT2AHTT | |
| SCHEMBL21605968 | 0.78 | ALDH1A1 (0.44) | POLBKMT2AALDH1A1HTTRECQL | |
| SCHEMBL27432573 | 0.78 | PKM (0.46) | POLBALDH1A1HTTRECQLNPC1 | |
| SCHEMBL27435059 | 0.77 | AR (0.47) | POLBARDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121130-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024121130-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2024-06-13 | — | — | WO | disclosed |