Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285310 | 1.00 | JAK1 (0.41) | JAK1EGFRSRCCYP3A4GPR119 | |
| SCHEMBL25240038 | 0.88 | HTR6 (0.43) | JAK1EGFRSRCPIK3CAHTR6 | |
| SCHEMBL29460624 | 0.88 | HTR6 (0.43) | JAK1EGFRSRCPIK3CAHTR6 | |
| SCHEMBL25284995 | 0.88 | HTR6 (0.43) | JAK1EGFRSRCPIK3CAHTR6 | |
| SCHEMBL2272937 | 0.88 | HTR6 (0.43) | JAK1EGFRSRCPIK3CAHTR6 | |
| SCHEMBL2284399 | 0.84 | JAK1 (0.47) | JAK1EGFRSRCHTR6BCHE | |
| SCHEMBL2224575 | 0.84 | HTR6 (0.46) | JAK1CYP3A4GPR119NR3C1HTR6 | |
| SCHEMBL29460614 | 0.81 | JAK1 (0.42) | JAK1CYP3A4HTR6 | |
| SCHEMBL29100337 | 0.81 | JAK1 (0.42) | JAK1CYP3A4HTR6 | |
| SCHEMBL29100338 | 0.81 | JAK1 (0.42) | JAK1CYP3A4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |