Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433963 | 1.00 | MAPT (0.40) | MAPTS1PR4SCN9ATDP1L3MBTL1 | |
| SCHEMBL30966104 | 0.85 | MAPT (0.46) | MAPTTDP1L3MBTL1RAB9AMAOB | |
| SCHEMBL27433301 | 0.85 | MAPT (0.46) | MAPTTDP1L3MBTL1RAB9AMAOB | |
| SCHEMBL27434442 | 0.83 | MAPT (0.38) | MAPTS1PR4TDP1L3MBTL1HTT | |
| SCHEMBL30966109 | 0.83 | MAPT (0.38) | MAPTS1PR4TDP1L3MBTL1HTT | |
| SCHEMBL30966089 | 0.81 | MAOB (0.43) | MAPTL3MBTL1RAB9AMAOBMAOA | |
| SCHEMBL27433526 | 0.81 | MAPT (0.42) | MAPTTDP1L3MBTL1RAB9AMAOB | |
| SCHEMBL27433446 | 0.81 | MAOB (0.43) | MAPTL3MBTL1RAB9AMAOBMAOA | |
| SCHEMBL27141409 | 0.81 | PLA2G2A (0.46) | MAPTL3MBTL1MAOBMAOAKDM4E | |
| SCHEMBL29127993 | 0.79 | GAA (0.53) | MAPTHTTRAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638460-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING | Aculeus Therapeutics Pty Ltd (AU) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024130341-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING | Aculeus Therapeutics Pty Ltd (AU) | 2024-06-27 | — | — | WO | disclosed |