SCHEMBL27433481

SCHEMBL27433481

Cc1c(Cl)cc2c(c1Br)OCCN2C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.37
FGB P02675 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NOTUM Q6P988 1/20 0.33
PKM P14618 1/20 0.32
DRD2 P14416 2/20 0.32
HTR6 P50406 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13681627 0.84 L3MBTL1 (0.36) TP53L3MBTL1POLBTDP1NOTUM
SCHEMBL27433483 0.77 TP53 (0.38) TP53L3MBTL1FGBPOLBNOTUM
SCHEMBL31726005 0.76 HTR6 (0.35) TP53L3MBTL1FGBPOLBTDP1
SCHEMBL16803621 0.73 L3MBTL1 (0.39) TP53L3MBTL1FGBPOLBTDP1
SCHEMBL27433462 0.73 PDE3B (0.43) TDP1
SCHEMBL21245682 0.71 CSF1R (0.37) PKMHTR6KMT2A
SCHEMBL23729551 0.69 L3MBTL1 (0.37) TP53L3MBTL1FGBPOLBTDP1
SCHEMBL18652293 0.68 PKM (0.38) TP53L3MBTL1FGBPOLBTDP1
SCHEMBL30954119 0.68 NOTUM (0.38) TP53L3MBTL1POLBNOTUMPKM
SCHEMBL27432668 0.68 NOTUM (0.38) TP53L3MBTL1POLBNOTUMPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed