Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954135 | 1.00 | POLB (0.44) | POLBGAAALDH1A1MAPTALOX15 | |
| SCHEMBL30954045 | 0.91 | POLB (0.42) | POLBGAAALDH1A1MAPTALOX15 | |
| SCHEMBL27433854 | 0.91 | POLB (0.42) | POLBGAAALDH1A1MAPTALOX15 | |
| SCHEMBL27435508 | 0.86 | DRD3 (0.41) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27435408 | 0.84 | HSP90AA1 (0.40) | GAAALDH1A1HSP90AA1HSP90B1L3MBTL1 | |
| SCHEMBL27435244 | 0.83 | TP53 (0.43) | ALDH1A1MAPTMAPK1KDM4EMEN1 | |
| SCHEMBL27435439 | 0.83 | HSP90B1 (0.44) | HSP90AA1HSP90B1MAPK1USP2KMT2A | |
| SCHEMBL27435327 | 0.82 | DRD2 (0.40) | MAPK1KDM4EMEN1KMT2A | |
| SCHEMBL27435364 | 0.80 | KCNA3 (0.42) | ALDH1A1MAPK1KDM4ETSHR | |
| SCHEMBL27434615 | 0.78 | ACACB (0.32) | MAPTALOX15HSP90AA1HSP90B1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121130-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2024-06-13 | — | — | WO | disclosed |