Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 5/20 | 0.41 |
| ▸ | FURIN | P09958 | 3/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 4/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27434235 | 1.00 | FAP (0.41) | FAPFURINSYKNPY4RNPY5R | |
| SCHEMBL27434329 | 1.00 | FAP (0.41) | FAPFURINSYKNPY4RNPY5R | |
| SCHEMBL23347019 | 0.92 | FAP (0.42) | FAPFURINIL23RMAP1LC3B | |
| SCHEMBL23330065 | 0.92 | FAP (0.42) | FAPFURINIL23RMAP1LC3B | |
| SCHEMBL23347020 | 0.92 | FAP (0.42) | FAPFURINIL23RMAP1LC3B | |
| SCHEMBL25094984 | 0.91 | FAP (0.42) | FAPFURINMAP1LC3B | |
| SCHEMBL23347018 | 0.91 | FAP (0.42) | FAPFURINIL23RMAP1LC3B | |
| SCHEMBL24829369 | 0.91 | FAP (0.42) | FAPFURINMAP1LC3B | |
| SCHEMBL25094954 | 0.90 | FAP (0.41) | FAPFURINMAP1LC3B | |
| SCHEMBL24164693 | 0.90 | FAP (0.41) | FAPFURINSYKIL23RMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | NR3C1, NR3C2, MC2R | FAP 1971/4885FURIN 4013/4885SYK 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.