Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954115 | 0.96 | MAPT (0.36) | MAPTKDM4EPKMNAAADGAT1 | |
| SCHEMBL27434123 | 0.94 | MAPT (0.40) | MAPTKDM4EPKMDGAT1SOAT1 | |
| SCHEMBL30954086 | 0.92 | MAPT (0.35) | MAPTKDM4EPKMNAAADGAT1 | |
| SCHEMBL30954165 | 0.91 | MAPT (0.38) | MAPTKDM4EPKMDGAT1SOAT1 | |
| SCHEMBL30954061 | 0.87 | NAAA (0.42) | NAAADRD2 | |
| SCHEMBL27434250 | 0.87 | NAAA (0.42) | NAAADRD2 | |
| SCHEMBL30954159 | 0.86 | MAPT (0.36) | MAPTKDM4EPKMDGAT1SOAT1 | |
| SCHEMBL30954149 | 0.84 | HTR4 (0.37) | MAPTDGAT1SOAT1LMNA | |
| SCHEMBL27434185 | 0.84 | HTR4 (0.37) | MAPTDGAT1SOAT1LMNA | |
| SCHEMBL27434257 | 0.82 | TSHR (0.38) | MAPTDGAT1SOAT1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121130-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2024-06-13 | — | — | WO | disclosed |