SCHEMBL30954061

SCHEMBL30954061

O=C(O)c1c(F)c(Cl)cc2c1OCCN2CCCc1ccc(F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.42
DRD2 P14416 4/20 0.38
LIPG Q9Y5X9 2/20 0.37
SIGMAR1 Q99720 2/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
HTR1A P08908 2/20 0.35
HTR2A P28223 2/20 0.35
HTR7 P34969 2/20 0.35
HRH1 P35367 2/20 0.35
SLC6A4 P31645 2/20 0.35
DRD1 P21728 1/20 0.35
DRD5 P21918 1/20 0.35
SLC6A2 P23975 1/20 0.35
DRD3 P35462 1/20 0.35
HTR2B P41595 1/20 0.35
CYSLTR2 Q9NS75 1/20 0.35
CYSLTR1 Q9Y271 1/20 0.35
PTGER4 P35408 1/20 0.35
PTGER2 P43116 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27434250 1.00 NAAA (0.42) NAAADRD2LIPGSIGMAR1HPGD
SCHEMBL30954112 0.94 NAAA (0.38) NAAALIPGHPGDTSHRHTR2A
SCHEMBL27434139 0.94 NAAA (0.38) NAAALIPGHPGDTSHRHTR2A
SCHEMBL30954115 0.92 MAPT (0.36) NAAADRD2
SCHEMBL27434239 0.87 MAPT (0.39) NAAADRD2
SCHEMBL30954165 0.86 MAPT (0.38) TSHR
SCHEMBL30954145 0.81 AR (0.36) DRD2HPGDTSHRDRD3HTR2C
SCHEMBL27434163 0.81 AR (0.36) DRD2HPGDTSHRDRD3HTR2C
SCHEMBL27434074 0.81 AR (0.41) SIGMAR1HPGDTSHRHDAC1HDAC6
SCHEMBL30954063 0.81 HTR4 (0.38) TSHRHTR1ACYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP claimed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO claimed
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed