Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887533 | 0.81 | MGLL (0.38) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| SCHEMBL155452 | 0.77 | MGLL (0.35) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| SCHEMBL27433355 | 0.74 | MGLL (0.32) | MGLLGSK3AGSK3B | |
| SCHEMBL4896905 | 0.72 | GSK3A (0.31) | MGLLGSK3AGSK3B | |
| SCHEMBL43978 | 0.69 | MGLL (0.45) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| SCHEMBL29017 | 0.69 | MGLL (0.45) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| SCHEMBL27458810 | 0.69 | CA1 (0.42) | MGLLALDH1A1LMNAMAPT | |
| SCHEMBL24024169 | 0.65 | MGLL (0.41) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| SCHEMBL22289873 | 0.65 | MGLL (0.41) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| SCHEMBL13968985 | 0.65 | MGLL (0.41) | MGLLGSK3AGSK3BGMNNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125448-A | 14-substituted marcfortines and derivatives useful as antiparasitic agents | UPJOHN CO (US) | 1996-06-26 | — | — | CN | claimed |
| CN-1125448-A | 14-substituted marcfortines and derivatives useful as antiparasitic agents | UPJOHN CO (US) | 1996-06-26 | — | — | CN | disclosed |