SCHEMBL27435302

SCHEMBL27435302

COc1c(Cl)cc2c(c1C(=O)O)OCCN2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TPMT P51580 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34
DHFR P00374 1/20 0.33
GAA P10253 2/20 0.33
TSHR P16473 1/20 0.33
DRD2 P14416 2/20 0.32
DRD3 P35462 2/20 0.32
REN P00797 1/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
CCR2 P41597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27433604 0.88 TAS1R3 (0.36) ALDH1A1KDM4EHSD17B10TPMTTAS1R3
SCHEMBL30954087 0.88 TAS1R3 (0.36) ALDH1A1KDM4EHSD17B10TPMTTAS1R3
SCHEMBL27432616 0.81 EGFR (0.34) ALDH1A1KDM4EHSD17B10GAAMAPT
SCHEMBL27432422 0.78 ALDH1A1 (0.49) ALDH1A1KDM4EHSD17B10TPMTTAS1R3
SCHEMBL27432600 0.77 EGFR (0.34) ALDH1A1KDM4EHSD17B10DHFRGAA
SCHEMBL30954101 0.77 EGFR (0.34) ALDH1A1KDM4EHSD17B10DHFRGAA
SCHEMBL7318609 0.74 HSD17B10 (0.36) ALDH1A1KDM4EHSD17B10TPMTTSHR
SCHEMBL27434417 0.73 MEN1 (0.33) KDM4EMAPTKMT2AMEN1
SCHEMBL30954108 0.73 KDM4E (0.43) ALDH1A1KDM4EHSD17B10TPMTTAS1R3
SCHEMBL27432464 0.73 KDM4E (0.43) ALDH1A1KDM4EHSD17B10TPMTTAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP claimed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO claimed
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed