SCHEMBL30954101

SCHEMBL30954101

COC(=O)c1c(F)c(Cl)cc2c1OCCN2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
TP53 P04637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 3/20 0.33
ENPP2 Q13822 1/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALPL P05186 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 2/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
RET P07949 1/20 0.31
NR4A2 P43354 1/20 0.31
PTGER3 P43115 1/20 0.31
DHFR P00374 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27432600 1.00 EGFR (0.34) EGFRLMNAMAPTTP53NPSR1
SCHEMBL27433604 0.87 TAS1R3 (0.36) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL30954087 0.87 TAS1R3 (0.36) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL27433652 0.86 NR1H2 (0.36) LMNAMAPTTP53NPSR1ALDH1A1
SCHEMBL30954084 0.86 NR1H2 (0.36) LMNAMAPTTP53NPSR1ALDH1A1
SCHEMBL27432616 0.85 EGFR (0.34) EGFRMAPTALDH1A1KDM4EGAA
SCHEMBL27433696 0.80 ALDH1A1 (0.40) ALDH1A1ENPP2SMN1; SMN2ALPLKDM4E
SCHEMBL27432579 0.80 EGFR (0.37) EGFRLMNAMAPTALDH1A1GAA
SCHEMBL27432592 0.79 ENPP2 (0.36) EGFRLMNAMAPTALDH1A1ENPP2
SCHEMBL27432951 0.79 ALDH1A1 (0.35) LMNAMAPTTP53NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed