SCHEMBL27435568

SCHEMBL27435568

Cc1ccc(-c2ccccc2O[Zr]Oc2ccccc2-c2ccc(C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.49
LMNA P02545 3/20 0.44
MAPK1 P28482 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
ALDH1A1 P00352 2/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
PTGS2 P35354 1/20 0.37
ENPP3 O14638 1/20 0.36
ENPP1 P22413 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27432940 0.83 MAPK1 (0.47) LMNAMAPK1L3MBTL1TDP1ALDH1A1
SCHEMBL11499533 0.81 SYK (0.53) SYKLMNAMAPK1L3MBTL1TDP1
SCHEMBL4425113 0.79 SYK (0.56) SYKLMNAMAPK1L3MBTL1TDP1
Hydrochloric Acid SCHEMBL27460503 0.78 ADRA2A (0.45) ADRA2AADRA2BADRA2CALDH1A1RAB9A
SCHEMBL8040741 0.78 SYK (0.50) SYKLMNAMAPK1L3MBTL1TDP1
SCHEMBL26509862 0.78 SYK (0.50) SYKLMNAMAPK1L3MBTL1TDP1
SCHEMBL8040823 0.76 SYK (0.49) SYKLMNAMAPK1L3MBTL1TDP1
SCHEMBL8036362 0.75 LMNA (0.50) SYKLMNAMAPK1TDP1ALDH1A1
SCHEMBL12999516 0.74 SYK (0.59) SYKLMNAMAPK1L3MBTL1TDP1
SCHEMBL1045874 0.74 FFAR4 (0.51) SYKL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1128817-C Solid catalyst for olefin polymerization and process for producing olefin polymer using the same MARUZEN PETROCHEM CO LTD (JP) 2003-11-26 CN disclosed