Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040823 | 0.98 | SYK (0.49) | SYKLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL9418893 | 0.87 | LMNA (0.47) | SYKLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL3874497 | 0.86 | SYK (0.46) | SYKLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL8040839 | 0.85 | SYK (0.45) | SYKLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL8040829 | 0.85 | SYK (0.45) | SYKLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL674709 | 0.85 | MAPK1 (0.47) | LMNAL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL11499533 | 0.83 | SYK (0.53) | SYKLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL3802449 | 0.81 | TSHR (0.39) | SYKLMNAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL4425113 | 0.81 | SYK (0.56) | SYKLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL26509862 | 0.79 | SYK (0.50) | SYKLMNAL3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438638-B1 | Process for producing norcamphane dicarbonitriles | MITSUI CHEMICALS INC (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-5087722-A | Catalytic hydrocyanation of bicyclo(2.2.1)-5-heptene-2-carbonitrile | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0438638-A1 | Process for producing norcamphane dicarbonitriles | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-31 | — | — | EP | disclosed |