Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Maleic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Anhydride SCHEMBL10544565 | 0.95 | FFAR3 (0.33) | FFAR3LCKFYN | |
| Maleic Anhydride SCHEMBL8745637 | 0.95 | FFAR3 (0.41) | FFAR3LCKFYNMIF | |
| Maleic Anhydride SCHEMBL3423046 | 0.92 | FFAR3 (0.39) | FFAR3LCKFYNMIF | |
| Maleic Anhydride SCHEMBL28171094 | 0.88 | FFAR3 (0.32) | FFAR3LCKFYN | |
| Maleic Anhydride SCHEMBL22831709 | 0.88 | TDP1 (0.31) | — | |
| Maleic Anhydride SCHEMBL11037404 | 0.86 | KMT2A (0.31) | — | |
| Maleic Anhydride SCHEMBL11078903 | 0.86 | LMNA (0.43) | FFAR3LCKFYN | |
| Maleic Anhydride SCHEMBL28056201 | 0.86 | ALDH1A1 (0.31) | FFAR3LCKFYN | |
| Maleic Anhydride SCHEMBL1428433 | 0.85 | TDP1 (0.32) | — | |
| Maleic Anhydride SCHEMBL28247 | 0.83 | KMT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467465-A | A kind of preparation method of graphene modified ethylene acetate-copolymer-maleic anhydride flame-retardant leather retanning agent | 四川大学 | 2018-08-31 | — | — | CN | claimed |
| CN-108467465-A | A kind of preparation method of graphene modified ethylene acetate-copolymer-maleic anhydride flame-retardant leather retanning agent | 四川大学 | 2018-08-31 | — | — | CN | disclosed |
| CN-1109101-A | Process for tie-dyeing pig leather with sheep leather appearance | JUXING FUR AND LEATHER CO CHEN (CN) | 1995-09-27 | — | — | CN | disclosed |