Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Maleic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Anhydride SCHEMBL28129306 | 0.88 | — | — | |
| Maleic Anhydride SCHEMBL11078903 | 0.87 | LMNA (0.43) | ALDH1A1FFAR3LCKFYNMEN1 | |
| Maleic Anhydride SCHEMBL27435581 | 0.86 | FFAR3 (0.37) | FFAR3LCKFYN | |
| Maleic Anhydride SCHEMBL8745637 | 0.86 | FFAR3 (0.41) | ALDH1A1FFAR3LCKFYNMEN1 | |
| Maleic Anhydride SCHEMBL3297855 | 0.86 | MEN1 (0.31) | ALDH1A1MEN1KMT2AATM | |
| Maleic Anhydride SCHEMBL3423046 | 0.84 | FFAR3 (0.39) | FFAR3LCKFYNMEN1KMT2A | |
| Maleic Anhydride SCHEMBL133505 | 0.83 | — | — | |
| Maleic Anhydride SCHEMBL10544565 | 0.82 | FFAR3 (0.33) | FFAR3LCKFYN | |
| Maleic Anhydride SCHEMBL8758569 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AATM | |
| Maleic Anhydride SCHEMBL29267683 | 0.81 | LMNA (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574786-A | Preparation method and use method of low-temperature plasticized orthopedic gloves | 安徽攀望科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-102455614-B | Electrostatic latent image developer, formation method and imaging device | FUJI XEROX CORP. (JP) | 2016-03-30 | — | — | CN | disclosed |