Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 5/20 | 0.45 |
| ▸ | HTR1D | P28221 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23817954 | 0.89 | ALDH1A1 (0.50) | KMT2AMEN1HTR1BHTR1DALDH1A1 | |
| SCHEMBL2207115 | 0.80 | HTR1A (0.50) | KMT2AMEN1HTR1BHTR1DALDH1A1 | |
| SCHEMBL20939751 | 0.78 | HTR1A (0.48) | KMT2AMEN1HTR1BHTR1DALDH1A1 | |
| SCHEMBL25455118 | 0.77 | LMNA (0.58) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL27165463 | 0.76 | BIRC2 (0.60) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL13942396 | 0.72 | LMNA (0.44) | KMT2AMEN1HTR1BHTR1DLMNA | |
| SCHEMBL2203257 | 0.71 | LMNA (0.44) | HTR1BHTR1DALDH1A1LMNANPC1 | |
| SCHEMBL3463893 | 0.71 | MAPT (0.47) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL18763042 | 0.71 | SLC22A12 (0.58) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL27436767 | 0.71 | XIAP (0.56) | KMT2AMEN1ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133499-A1 | GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES | RHEINISCHE-FRIEDRICH-WILHELMS-UNIVERSITÄT BONN (DE) | 2024-06-27 | — | — | WO | disclosed |