SCHEMBL27437475

SCHEMBL27437475

NC(=O)N(n1ccnc1)[SH](=O)=O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
NFKB1 P19838 1/20 0.31
QPCT Q16769 1/20 0.31
HSD17B10 Q99714 1/20 0.31
QPCTL Q9NXS2 1/20 0.31
CYP3A4 P08684 1/20 0.31
BAZ2B Q9UIF8 1/20 0.31
EGLN3 Q9H6Z9 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218901 0.77 HTT (0.37) ALDH1A1HTTNFKB1QPCTHSD17B10
SCHEMBL10984244 0.76 ALDH1A1 (0.36) ALDH1A1HTTNFKB1QPCTHSD17B10
SCHEMBL28133712 0.76 CYP3A4 (0.35) ALDH1A1HTTNFKB1QPCTHSD17B10
SCHEMBL28102176 0.75 ALDH1A1 (0.35) ALDH1A1HTTNFKB1QPCTHSD17B10
SCHEMBL27752485 0.73 ALDH1A1 (0.34) ALDH1A1EGLN3
SCHEMBL28470760 0.70 FDPS (0.33) ALDH1A1EGLN3
SCHEMBL29118428 0.70 ALDH1A1 (0.32) ALDH1A1EGLN3
SCHEMBL27874750 0.70 CYP3A4 (0.39) ALDH1A1HTTNFKB1QPCTHSD17B10
SCHEMBL10853269 0.66 TBXAS1 (0.32) MAPT
SCHEMBL28386193 0.66 TSHR (0.41) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101674727-B Pyridonecarboxamides crop protection agents containing the same method for production and use thereof BAYER CROPSCIENCE AG 2014-06-25 CN disclosed
CN-100413848-C Acylsulfamoylbenzamides, crop protection compositions containing them and processes for their preparation HOECHST SCHERING AGREVO GMBH (DE) 2008-08-27 CN disclosed
CN-1481213-A Herbicide agent �Ϻ���ͨ��ѧ 2004-03-10 CN disclosed
CN-1102142-C Novel N-acyl sulphonamides, novel mixtures of herbicides and antidotes and their use HOECHST SCHERING AGREVO GMBH (DE) 2003-02-26 CN disclosed
CN-1219840-A Novel N-acyl sulphonamides, novel mixtures of herbicides and antidotes and their use HOECHST SCHERING AGREVO GMBH (DE) 1999-06-16 CN disclosed