Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | KIF11 | P52732 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1181301 | 0.84 | GAA (0.56) | KDM4EGAAGLAKIF11LMNA | |
| SCHEMBL1180269 | 0.83 | KDM4E (0.61) | KDM4EGAAGLAKIF11CA2 | |
| SCHEMBL27727218 | 0.80 | KDM4E (0.63) | KDM4EGAAGLAKIF11LMNA | |
| 7-Methoxy-3-Methylcarbazole SCHEMBL602038 | 0.80 | KDM4E (0.67) | KDM4EKIF11LMNAALDH1A1MEN1 | |
| 7-Methoxy-3-Methylcarbazole SCHEMBL31214611 | 0.80 | KDM4E (0.67) | KDM4EKIF11LMNAALDH1A1MEN1 | |
| SCHEMBL27848144 | 0.79 | KDM4E (0.52) | KDM4EGAAGLAKIF11LMNA | |
| SCHEMBL10141055 | 0.77 | KIF11 (0.75) | KDM4EGAAKIF11LMNAALDH1A1 | |
| SCHEMBL29726991 | 0.77 | KIF11 (0.75) | KDM4EGAAKIF11LMNAALDH1A1 | |
| SCHEMBL12986903 | 0.76 | KDM4E (1.00) | KDM4EGAAGLALMNACA2 | |
| SCHEMBL8352133 | 0.74 | KDM4E (0.51) | KDM4EGAAKIF11LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247558-B2 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | LILLY CO ELI (US) | 2024-07-03 | — | — | EP | disclosed |