Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772243 | 0.86 | GAA (0.54) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL4157986 | 0.83 | AKR1C2 (0.57) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL11667064 | 0.80 | GSK3B (0.54) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL8119091 | 0.77 | ABCB11 (0.43) | KDM4EALDH1A1MAPTGAAMEN1 | |
| Chlorobenzene SCHEMBL5800449 | 0.77 | GAA (0.45) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL27768656 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL20398612 | 0.75 | ABCB11 (0.53) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL30434152 | 0.75 | ABCB11 (0.53) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL20398581 | 0.75 | ABCB11 (0.53) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL22898798 | 0.75 | HSD17B10 (0.50) | KDM4EALDH1A1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032112-A1 | METHOD FOR TREATING DIABETES | ELI LILLY AND COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |