Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | KIF11 | P52732 | 4/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7-Methoxy-3-Methylcarbazole SCHEMBL31214611 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL6009651 | 0.91 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| Glycozoline SCHEMBL11981403 | 0.91 | ALDH1A1 (0.81) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| 7-Methoxy-3-Methylcarbazole SCHEMBL31214594 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL2330779 | 0.85 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL29533596 | 0.85 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL10141055 | 0.83 | KIF11 (0.75) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL29726991 | 0.83 | KIF11 (0.75) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL14598934 | 0.82 | ABCG2 (0.68) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL1180818 | 0.81 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247558-B2 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | LILLY CO ELI (US) | 2024-07-03 | — | — | EP | disclosed |
| EP-2247558-B1 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | LILLY CO ELI (US) | 2022-02-02 | — | — | EP | disclosed |
| CN-108659050-B | Tetradentate ring metal platinum complex containing 6-substituted carbazole, preparation method and application | 浙江工业大学 | 2021-03-09 | — | — | CN | disclosed |
| US-20190322928-A1 | TETRADENTATE CYCLIC-METAL PLATINUM COMPLEXES COMPRISING 6-SUBSTITUTED CARBAZOLE, PRERATION AND USE THEREOF | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2019-10-24 | — | — | US | disclosed |
| US-20190322928-A1 | TETRADENTATE CYCLIC-METAL PLATINUM COMPLEXES COMPRISING 6-SUBSTITUTED CARBAZOLE, PRERATION AND USE THEREOF | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2019-10-24 | — | — | US | disclosed |
| CN-108659050-A | Four ring gear metal platinum complexes, preparation method and application containing 6- substituted carbazoles | 浙江工业大学 | 2018-10-16 | — | — | CN | disclosed |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | THE UNIV OF MONTANA (US) | 2017-04-06 | — | — | US | disclosed |
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | CNR1, CNR2, OPRL1 | KDM4E 2223/4885ALDH1A1 4037/4885HSD17B10 2895/4885 |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | CNR1, CNR2, OPRL1 | KDM4E 2223/4885ALDH1A1 4037/4885HSD17B10 2895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.