Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264201 | 0.75 | MAOA (0.46) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL16728889 | 0.74 | MAOA (0.45) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL29814962 | 0.74 | MAOA (0.45) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL347425 | 0.74 | MAOA (0.45) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL27516784 | 0.73 | MAOA (0.41) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL7138108 | 0.72 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL1156077 | 0.72 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL31571121 | 0.72 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL32662573 | 0.72 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2NOX1BCHE | |
| SCHEMBL4580436 | 0.72 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2NOX1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202819-C | Intraocular pressure reducing agent | SANKYO CO (JP) | 2005-05-25 | — | — | CN | disclosed |
| CN-1104898-C | intraocular pressure lowering agent | SANKYO CO (JP) | 2003-04-09 | — | — | CN | disclosed |
| CN-1387846-A | Intraocular pressure reducing agent | SANKYO CO (JP) | 2003-01-01 | — | — | CN | disclosed |
| CN-1284070-A | Alicyclic acylated heterocyclic derivatives | SANKYO CO (JP) | 2001-02-14 | — | — | CN | disclosed |
| CN-1148809-A | intraocular pressure lowering agent | SANKYO CO (JP) | 1997-04-30 | — | — | CN | disclosed |