Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024602 | 0.87 | ALDH1A1 (0.49) | PRSS1TPSAB1ACHEALDH1A1HPGD | |
| SCHEMBL25964314 | 0.84 | PRSS1 (0.46) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL16015346 | 0.81 | PRSS1 (0.48) | PRSS1TPSAB1ACHEALDH1A1HPGD | |
| SCHEMBL25964144 | 0.81 | PRSS1 (0.43) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL24797627 | 0.79 | PRSS1 (0.45) | PRSS1TPSAB1ACHEALDH1A1HPGD | |
| SCHEMBL25749356 | 0.78 | PRSS1 (0.41) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL1329140 | 0.77 | HDAC1 (0.52) | PRSS1TPSAB1ACHEALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8696150 | 0.76 | HDAC1 (0.51) | PRSS1TPSAB1ACHEALDH1A1HPGD | |
| SCHEMBL20794169 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL1880511 | 0.76 | HDAC1 (0.51) | PRSS1TPSAB1ACHEALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141575-A1 | ANTIBODY-DRUG CONJUGATES TARGETING UPARAP COMPRISING EXATECAN DERIVATIVES | ADCENDO APS (DK) | 2024-07-04 | — | — | WO | disclosed |