Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808474 | 0.86 | CNR1 (0.58) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL359405 | 0.84 | MAPT (0.59) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27440837 | 0.83 | MAPT (0.57) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL27537456 | 0.83 | CHEK1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12995581 | 0.83 | CNR1 (0.50) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL321164 | 0.83 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27480007 | 0.83 | MAPT (0.68) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5974338 | 0.82 | MAPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL29952991 | 0.82 | MAPT (0.60) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL321590 | 0.81 | MAOA (0.53) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098070-C | Guanylhydrazones for treating inflammatory conditions | PICOWER INST MED RES (US) | 2003-01-08 | — | — | CN | disclosed |
| CN-1144480-A | Guanylhydrazones for treating inflammatory conditions | PICOWER INST MED RES (US) | 1997-03-05 | — | — | CN | disclosed |