Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957192 | 0.91 | EPHX2 (0.58) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL27183437 | 0.87 | S1PR1 (0.57) | NPC1SMN1; SMN2RAB9AS1PR1ALDH1A1 | |
| SCHEMBL29951995 | 0.83 | MAPT (0.64) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL29956830 | 0.83 | MAPT (0.67) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL27440837 | 0.82 | MAPT (0.57) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL27439714 | 0.82 | MAPT (0.57) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL20335072 | 0.81 | ITGB3 (0.63) | NPC1SMN1; SMN2RAB9AS1PR1ALDH1A1 | |
| SCHEMBL5974338 | 0.81 | MAPT (0.56) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL19428148 | 0.80 | FOLH1 (0.60) | SMN1; SMN2RAB9AS1PR1MEN1KMT2A | |
| SCHEMBL2644934 | 0.80 | CA1 (0.61) | NPC1RAB9AALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |