Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713974 | 0.81 | ESR1 (0.49) | ESR1ESR2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL23119878 | 0.80 | SMN1; SMN2 (0.56) | PKMSMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL6711049 | 0.76 | ESR1 (0.56) | ESR1ESR2FFAR4LMNA | |
| SCHEMBL11247022 | 0.75 | ALDH1A1 (0.47) | PKMESR1ESR2SMN1; SMN2ALDH1A1 | |
| Methane SCHEMBL27462098 | 0.74 | ESR1 (0.54) | ESR1ESR2FFAR4LMNA | |
| SCHEMBL68340 | 0.73 | PKM (0.60) | PKMSMN1; SMN2ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL11244680 | 0.73 | FFAR4 (0.64) | PKMESR1ESR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2390130 | 0.73 | CYP4F2 (0.51) | PKMSMN1; SMN2ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL3135580 | 0.72 | MAOB (0.56) | PKMSMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL933225 | 0.71 | ESR1 (0.50) | ESR1ESR2FFAR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1139580-C | Substituted benzylamines and their use for the treatment of depression | ��˹��ŵ�� | 2004-02-25 | — | — | CN | disclosed |
| CN-1219169-A | Substituted benzylamines and their use for the treatment of depression | AKZO NOBEL NV (NL) | 1999-06-09 | — | — | CN | disclosed |