Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18475349 | 0.82 | TLR8 (0.51) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL1544861 | 0.82 | TLR8 (0.48) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL1545308 | 0.82 | TLR8 (0.48) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL1748737 | 0.75 | TLR8 (0.60) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL17429741 | 0.73 | PDE3B (0.50) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL7866316 | 0.73 | CSNK2A1 (0.55) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL7756643 | 0.72 | NR4A2 (0.43) | NR4A2 | |
| SCHEMBL622083 | 0.71 | GPR84 (0.38) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL187054 | 0.71 | TLR8 (0.55) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL8792772 | 0.71 | SLC6A4 (0.47) | POLBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136275-A | Arylheterocyclylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics | HOECHST ROUSSEL PHARMA (US) | 1996-11-20 | — | — | CN | disclosed |