Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.33 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.33 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986942 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL5987722 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL19248240 | 0.73 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL17324284 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL19248241 | 0.71 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL17321061 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL12546006 | 0.70 | CHRNB2 (0.39) | CYP1A2IKBKETBK1 | |
| SCHEMBL8404362 | 0.69 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL12051645 | 0.69 | EIF4A3 (0.38) | POLBLMNAEIF4A3 | |
| SCHEMBL17321031 | 0.69 | ALOX15 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | KDM1A, TET1, KDM3A | ALDH1A1 460/4885KDM4E 40/4885HSD17B10 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.