Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744232 | 0.94 | TUBB1 (0.54) | TUBB1ALDH1A1MAPK1FDPSHPGD | |
| SCHEMBL7122419 | 0.85 | TUBB1 (0.49) | TUBB1ALDH1A1MAPK1FDPSHPGD | |
| SCHEMBL13168474 | 0.85 | FDPS (0.50) | TUBB1ALDH1A1MAPK1FDPSHPGD | |
| SCHEMBL19737048 | 0.84 | TUBB1 (0.50) | TUBB1ALDH1A1MAPK1FDPSHPGD | |
| SCHEMBL9153088 | 0.84 | ALDH1A1 (0.67) | TUBB1ALDH1A1MAPK1FDPSHPGD | |
| SCHEMBL15771884 | 0.84 | ALDH1A1 (0.51) | TUBB1ALDH1A1MAPK1FDPSHPGD | |
| SCHEMBL14723251 | 0.83 | TUBB1 (0.49) | TUBB1ALDH1A1MAPK1FDPSHPGD | |
| Syringaldehyde SCHEMBL28294707 | 0.82 | ALDH1A1 (0.55) | TUBB1ERN1ALDH1A1FDPSHPGD | |
| Syringaldehyde SCHEMBL150376 | 0.82 | ALDH1A1 (0.62) | TUBB1ERN1ALDH1A1FDPSHPGD | |
| Syringaldehyde SCHEMBL30119623 | 0.82 | ALDH1A1 (0.62) | TUBB1ERN1ALDH1A1FDPSHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574510-A4 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | INNOVATIVE TECH CENTER (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0574510-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1993-12-22 | — | — | EP | disclosed |