Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | F7 | P08709 | 3/20 | 0.45 |
| ▸ | F3 | P13726 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744091 | 1.00 | TRPA1 (0.59) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL4664269 | 1.00 | TRPA1 (0.59) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL8579054 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL309546 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL28393973 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL3110731 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL8816152 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL18954266 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL1116445 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG | |
| SCHEMBL309545 | 0.93 | TRPA1 (0.68) | TRPA1PPARAALDH1A1CYP19A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016116634-A1 | PROCESS FOR THE PREPARATION OF A POLYUNSATURATED KETONE COMPOUND | AVEXXIN AS (NO) | 2016-07-28 | — | — | WO | disclosed |
| US-20160159737-A1 | PROCESS FOR THE PREPARATION OF A POLYUNSATURATED KETONE COMPOUND | AVEXXIN AS (NO) | 2016-06-09 | — | — | US | disclosed |
| US-20160159737-A1 | PROCESS FOR THE PREPARATION OF A POLYUNSATURATED KETONE COMPOUND | AVEXXIN AS (NO) | 2016-06-09 | — | — | US | disclosed |
| WO-2015011206-A1 | PROCESS FOR THE PREPARATION OF A POLYUNSATURATED KETONE COMPOUND | AVEXXIN AS (NO) | 2015-01-29 | — | — | WO | disclosed |
| US-20120232143-A1 | LIPID DERIVATIVES | PRONOVA BIOPHARMA NORGE AS | 2012-09-13 | — | — | US | disclosed |
| US-8178708-B2 | Lipid derivatives | PRONOVA BIOPHARMA NORGE AS (NO) | 2012-05-15 | — | — | US | disclosed |
| US-20090105499-A1 | LIPID DERIVATIVES | PRONOVA BIOPHARMA NORGE AS (NO) | 2009-04-23 | — | — | US | disclosed |
| EP-2007702-A2 | CONJUGATED LIPID DERIVATIVES | Pronova BioPharma Norge AS (NO) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007107869-A2 | LIPID DERIVATIVES | PRONOVA BIOPHARMA NORGE AS (NO) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232143-A1 | LIPID DERIVATIVES | CYP4F3, STARD3, PLIN3 | TRPA1 3872/4885PPARA 802/4885ALDH1A1 1254/4885 |
| US-20090105499-A1 | LIPID DERIVATIVES | PLIN3, STARD3, CYP4F3 | TRPA1 3908/4885PPARA 885/4885ALDH1A1 1511/4885 |
| US-20160159737-A1 | PROCESS FOR THE PREPARATION OF A POLYUNSATURATED KETONE COMPOUND | ALOX15, FADS1, FASN | TRPA1 3548/4885PPARA 72/4885ALDH1A1 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.