Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.60 |
| ▸ | ACE | P12821 | 5/20 | 0.60 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27444751 | 0.96 | MME (0.55) | MMEACETACR1HRH4CPA1 | |
| SCHEMBL8030487 | 0.89 | ACE (0.74) | MMEACEHRH4CPA1ACE2 | |
| SCHEMBL8029478 | 0.88 | MME (0.59) | MMEACETACR1HRH4CPA1 | |
| SCHEMBL27446785 | 0.87 | MME (0.80) | MMEACETACR1HRH4CPA1 | |
| SCHEMBL8027391 | 0.87 | MME (0.80) | MMEACETACR1HRH4CPA1 | |
| SCHEMBL8027402 | 0.87 | ACE (0.48) | MMEACECPA1ACE2OPRM1 | |
| SCHEMBL8017737 | 0.85 | ACE (0.64) | MMEACETACR1HRH4CPA1 | |
| SCHEMBL8030684 | 0.84 | MME (0.62) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL27547830 | 0.84 | TACR1 (0.57) | MMEACETACR1HRH4CPA1 | |
| SCHEMBL8017176 | 0.84 | MME (0.59) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |