Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.58 |
| ▸ | PLK1 | P53350 | 2/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 4/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25338138 | 0.84 | PIK3CA (0.55) | PIK3CGPIK3CAPIK3CBPLK1CLK1 | |
| SCHEMBL31118851 | 0.84 | PIK3CA (0.55) | PIK3CGPIK3CAPIK3CBPLK1CLK1 | |
| SCHEMBL27445357 | 0.81 | PIK3CG (0.57) | PIK3CGPIK3CAPIK3CBPLK1IKBKB | |
| SCHEMBL27445382 | 0.80 | PLK1 (0.56) | PIK3CGPIK3CAPIK3CBPLK1CLK1 | |
| SCHEMBL27446266 | 0.80 | PLK1 (0.77) | PIK3CGPIK3CAPLK1MEN1NPC1 | |
| SCHEMBL7470313 | 0.76 | ABL1 (0.58) | PIK3CGPIK3CAPIK3CBMEN1NPC1 | |
| SCHEMBL4735987 | 0.75 | PIK3CA (0.68) | PIK3CGPIK3CAPIK3CBPLK1CLK1 | |
| SCHEMBL27445456 | 0.75 | PLK1 (0.57) | PIK3CGPIK3CAPIK3CBPLK1RAB9A | |
| SCHEMBL4784122 | 0.75 | PIK3CA (0.64) | PIK3CGPIK3CAPIK3CBPLK1CLK1 | |
| SCHEMBL16404646 | 0.74 | CLK4 (0.81) | CLK1DYRK1ACLK4DYRK1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | PIK3CG 4501/4885PIK3CA 4141/4885PIK3CB 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.