Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 7/20 | 0.57 |
| ▸ | CDK4 | P11802 | 7/20 | 0.57 |
| ▸ | CDK2 | P24941 | 7/20 | 0.57 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27445357 | 0.86 | PIK3CG (0.57) | PLK1CDK4CDK2CDK1CCNB2 | |
| SCHEMBL25338224 | 0.84 | SYK (0.56) | PLK1CDK4CDK2CDK1CCNB1 | |
| SCHEMBL31119036 | 0.84 | SYK (0.56) | PLK1CDK4CDK2CDK1CCNB1 | |
| SCHEMBL25336514 | 0.82 | CDK1 (0.58) | PLK1CDK4CDK2CDK1CCNB2 | |
| SCHEMBL31118931 | 0.82 | CDK1 (0.58) | PLK1CDK4CDK2CDK1CCNB2 | |
| SCHEMBL27444251 | 0.81 | IKBKB (0.52) | CDK4CDK2CDK1CCNB2CCNB1 | |
| SCHEMBL27446674 | 0.80 | PLK1 (0.53) | PLK1CDK4CDK2CDK1CCNB2 | |
| SCHEMBL27445373 | 0.75 | PIK3CG (0.58) | PLK1CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL27446583 | 0.74 | CDK1 (0.47) | PLK1CDK4CDK2CDK1CCNB2 | |
| SCHEMBL27444532 | 0.74 | CDK9 (0.49) | PLK1CDK4CDK2CDK1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | PLK1 4810/4885CDK4 3495/4885CDK2 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.