Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KHK | P50053 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504558 | 0.83 | ALDH1A1 (0.44) | CDK4ALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL3475236 | 0.83 | ALDH1A1 (0.44) | CDK4ALDH1A1HSD17B10KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL27602949 | 0.77 | KHK (0.45) | ALDH1A1HSD17B10KDM4ELMNAHPGD | |
| SCHEMBL27421056 | 0.74 | KDR (0.42) | ALDH1A1HSD17B10KDM4ELMNAHPGD | |
| SCHEMBL18426583 | 0.70 | LMNA (0.44) | CDK4ALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL10922225 | 0.69 | KDM4E (0.42) | ALDH1A1HSD17B10KDM4ELMNAHPGD | |
| SCHEMBL7011234 | 0.67 | KDM4E (0.52) | ALDH1A1HSD17B10KDM4ELMNAHPGD | |
| Hydrochloric Acid SCHEMBL27411367 | 0.66 | KDM4E (0.36) | CDK4CDK6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL25377498 | 0.66 | MEN1 (0.40) | KHKDRD3HTR6 | |
| SCHEMBL27670321 | 0.65 | LMNA (0.53) | ALDH1A1HSD17B10KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1099029-A | Carbostyril carboxylic acid derivatives, its preparation and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-02-22 | — | — | CN | disclosed |