Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254518 | 0.88 | LMNA (0.51) | LMNAMAPTPKMSMN1; SMN2NPSR1 | |
| SCHEMBL6268897 | 0.86 | LMNA (0.46) | LMNAMAPTPKMSMN1; SMN2NPSR1 | |
| SCHEMBL27462030 | 0.86 | LMNA (0.51) | LMNAMAPTPKMSMN1; SMN2NPSR1 | |
| SCHEMBL27620312 | 0.85 | LMNA (0.45) | LMNAMAPTPKMSMN1; SMN2NPSR1 | |
| SCHEMBL27639213 | 0.82 | LMNA (0.44) | LMNAMAPTPKMSMN1; SMN2NPSR1 | |
| SCHEMBL6270137 | 0.81 | LMNA (0.45) | LMNAMAPTPKMSMN1; SMN2NPSR1 | |
| SCHEMBL6253936 | 0.80 | LMNA (0.44) | LMNAMAPTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL5070301 | 0.79 | GPR55 (0.46) | LMNAMAPTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL27441895 | 0.77 | ALDH1A1 (0.45) | LMNAMAPTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL27441898 | 0.77 | ALDH1A1 (0.45) | LMNAMAPTPKMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1742013-A | Pyrazolopyrimidine compound and method for producing the same | TANABE SEIYAKU CO (JP) | 2006-03-01 | — | — | CN | claimed |
| CN-1123028-A | Fungicidal fused bicyclic pyrimidinones | DU PONT (US) | 1996-05-22 | — | — | CN | disclosed |