Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 6/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658617 | 0.75 | IDO1 (0.34) | AR | |
| SCHEMBL102596 | 0.70 | CBFB (0.37) | — | |
| SCHEMBL27751481 | 0.69 | BRD4 (0.44) | HTT | |
| Water SCHEMBL28270232 | 0.69 | CBFB (0.36) | — | |
| SCHEMBL283897 | 0.68 | — | — | |
| SCHEMBL3259924 | 0.67 | — | — | |
| SCHEMBL25672720 | 0.67 | HRH4 (0.35) | — | |
| SCHEMBL8622721 | 0.67 | ADRB2 (0.33) | HTT | |
| SCHEMBL2291635 | 0.67 | RPS6KA3 (0.44) | JAK2 | |
| SCHEMBL6052024 | 0.67 | MMP2 (0.59) | GLO1ALOX15HTTCHEK1CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118797-A | Embossing inhibitor | ARMSTRONG WORLD IND INC (US) | 1996-03-20 | — | — | CN | claimed |
| CN-1118797-A | Embossing inhibitor | ARMSTRONG WORLD IND INC (US) | 1996-03-20 | — | — | CN | disclosed |